Jon Jay hit an RBI single with two out in the eighth inning to break a tie and lead the St. Louis Cardinals to a 3-2 win over the Boston Red Sox on Tuesday night.
The Cardinals won their third in a row and fourth in the last five. Boston has lost three in a row.
Jay, who missed the previous five games with a wrist injury, blooped a hit to left off reliever Junichi Tazawa (1-3) to bring in former Red Sox A.J. Pierzynski with the winning run.
Reliever Pat Neshek (5-0) picked up the win by striking out the side in the eighth.
St. Louis closer Trevor Rosenthal recorded his NL-leading 35th save in 39 chances.
Boston beat St. Louis in six games in last year's World Series.