Friday's contest features the St. Louis Cardinals (23-29) and the Cleveland Guardians (21-28) matching up at Progressive Field in what is expected to be a competitive matchup, with a projected 5-3 win for the Cardinals according to our computer prediction. Game time is at 7:10 PM ET on May 26.

This contest's pitching matchup is set, as the Guardians will send Shane Bieber (3-3) to the mound, while Matthew Liberatore (1-0) will get the nod for the Cardinals.

Cardinals vs. Guardians Game Info & Odds

  • When: Friday, May 26, 2023 at 7:10 PM ET
  • Where: Progressive Field in Cleveland, Ohio
  • How to Watch on TV: BSGL
  • Live Stream: Watch this game on Fubo!

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Cardinals vs. Guardians Score Prediction

Our pick for this contest is Cardinals 5, Guardians 4.

Total Prediction for Cardinals vs. Guardians

  • Total Prediction: Over 7.5 runs

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Explore More About This Game

Cardinals Performance Insights

  • In three games as the underdog over the last 10 matchups, the Cardinals have posted a mark of 2-1.
  • When it comes to the over/under, St. Louis and its foes are 6-4-0 in its previous 10 contests.
  • The last 10 Cardinals matchups have not had a runline set by oddsmakers.
  • The Cardinals have won in nine, or 45%, of the 20 contests they have been named as odds-on underdogs this year.
  • This season, St. Louis has come away with a win seven times in 16 chances when named as an underdog of at least -105 or longer on the moneyline.
  • The moneyline set for this matchup implies the Cardinals have a 51.2% chance of coming away with a victory in the contest.
  • The offense for St. Louis is No. 4 in baseball, scoring 5.1 runs per game (263 total runs).
  • The Cardinals have pitched to a 4.34 ERA this season, which ranks 18th in baseball.

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Cardinals Schedule

Date Opponent Score Pitching Matchup
May 21 Dodgers W 10-5 Jack Flaherty vs Clayton Kershaw
May 22 @ Reds L 6-5 Jordan Montgomery vs Brandon Williamson
May 23 @ Reds W 8-5 Adam Wainwright vs Graham Ashcraft
May 24 @ Reds L 10-3 Steven Matz vs Ben Lively
May 25 @ Reds W 2-1 Miles Mikolas vs Luke Weaver
May 26 @ Guardians - Matthew Liberatore vs Shane Bieber
May 27 @ Guardians - Jack Flaherty vs Tanner Bibee
May 28 @ Guardians - Jordan Montgomery vs Hunter Gaddis
May 29 Royals - Adam Wainwright vs TBA
May 30 Royals - Steven Matz vs Zack Greinke
June 2 @ Pirates - Miles Mikolas vs Roansy Contreras